Description:
TC-E3 5032 is a linker used in PROTAC technology that can be used in the synthesis of HDAC6 and anaplastic lymphoma kinase (ALK) degraders.
- Molecular Weight: 276.22
- Molecular Formula: C13H9FN2O4
Purity: ≥ 98%
Canonical SMILES:
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)F
InChI:
InChI=1S/C13H9FN2O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5H2,(H,15,17,18)
InChIKey: CRAUTELYXAAAPW-UHFFFAOYSA-N
- Boiling Point: 520.9±45.0 °C (Predicted)
- Melting Point: 254-256 °C
- Solubility: Slightly soluble in Dichloromethane (Heated), DMSO
- Appearance: White to Off-white Solid to Pale Purple Solid
- Storage: -20 °C
Synonyms:
E3 ligase Ligand 4; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro-; Thalidomide 4-fluoride; Thalidomide fluoride; 4-Fluoro-thalidomide; Cereblon ligand 4;E3 ligase Ligand 4; 2-(2,6-Dioxo-3-piperidinyl)-4-fluoro-1H-isoindole-1,3(2H)-dione
More details are to be found on supplier website
