Description:
DCPIB is a potent and selective volume-sensitive anion channel (VSAC) blocker, swell in various cardiovascular tissues (IC50 = 4.1 μM in CPAE cells). It inhibits glucose-stimulated insulin in intact β-cells, and reverses cell swelling-induced action potential duration shortening in atrial myocytes and inhibits astroglial swelling in vitro.
- Molecular Weight: 427.37
- Molecular Formula: C22H28Cl2O4
Purity: ≥98% by HPLC
Canonical SMILES:
CCCCC1(CC2=CC(=C(C(=C2C1=O)Cl)Cl)OCCCC(=O)O)C3CCCC3
InChI:
InChI=1S/C22H28Cl2O4/c1-2-3-10-22(15-7-4-5-8-15)13-14-12-16(28-11-6-9-17(25)26)19(23)20(24)18(14)21(22)27/h12,15H,2-11,13H2,1H3,(H,25,26)
InChIKey: KHKGTPJPBOQECW-UHFFFAOYSA-N
Synonyms:
4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]butanoic acid
More details are to be found on supplier website
