Description:
Sancycline is a tetracycline bacteriostatic antibiotic which also binds to the Tet repressor protein (TetR). Sancycline acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site.
- Molecular Weight: 414.41
- Molecular Formula: C21H22N2O7
Purity: >95%
Canonical SMILES:
CN(C)C1C2CC3CC4=C(C(=CC=C4)O)C(=C3C(=O)C2(C(=C(C1=O)C(=O)N)O)O)O
InChI:
InChI=1S/C21H22N2O7/c1-23(2)15-10-7-9-6-8-4-3-5-11(24)12(8)16(25)13(9)18(27)21(10,30)19(28)14(17(15)26)20(22)29/h3-5,9-10,15,24-25,28,30H,6-7H2,1-2H3,(H2,22,29)/t9-,10-,15-,21-/m0/s1
InChIKey: MTCQOMXDZUULRV-ADOAZJKMSA-N
- Boiling Point: 750.9°C at 760 mmHg
- Melting Point: 224-228°C (dec)
- Solubility: Soluble in DMSO (>10 mg/mL)
- Appearance: Off-white Solid
- Storage: Store at -20°C
Synonyms:
Minocycline EP Impurity B; 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide; Norcycline; Bonomycin
More details are to be found on supplier website
