Description:
Ursolic acid is a natural pentacyclic triterpenoid carboxylic acid displaying antitumor activity. It was shown to downregulate the MMP-2 and uPA expression, and also inhibit Na+/K+-ATPase activity (IC50 = 24.7 μM) as well as NF-κB activation in various cancer cell lines. Ursolic acid can induce apoptosis in cancer cells. Ursolic acid also has obvious antioxidant function, so it is widely used as a raw material for medicine and cosmetics.
- Molecular Weight: 456.711
- Molecular Formula: C30H48O3
Purity: ≥ 98%
Canonical SMILES:
CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1C)C)C(=O)O
InChI:
InChI=1S/C30H48O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1
InChIKey: WCGUUGGRBIKTOS-GPOJBZKASA-N
- Boiling Point: 556.9±50.0 °C at 760 mmHg
- Melting Point: 280-290 °C
- Solubility: About 0.5% in Ethanol, More than 2.5% in DMSO; Practically insoluble in water.
- Appearance: White powder
- Application: antidepressant
- Storage: Keep container tightly closed in a cool, dark and dry place.
Synonyms:
NSC-167406; NSC-4060; NSC167406; NSC4060; NSC 167406; NSC 4060; Malol; Prunol; Urson; 3beta-Hydroxyurs-12-en-28-oic acid
More details are to be found on supplier website