Description:
Kukoamine A is a spermine alkaloid isolated from Lycium chinense, potatoes, and tomatoes. It exhibits diverse biological activities, including anticancer, neuroprotective, and anti-inflammatory properties. Kukoamine A inhibits human glioblastoma cell growth and migration via apoptosis induction and epithelial-mesenchymal transition attenuation mediated by downregulating expressions of 5-LOX and C/EBPβ.
- Molecular Weight: 530.66
- Molecular Formula: C28H42N4O6
Purity: ≥95%
Canonical SMILES:
C1=CC(=C(C=C1CCC(=O)NCCCNCCCCNCCCNC(=O)CCC2=CC(=C(C=C2)O)O)O)O
InChI:
InChI=1S/C28H42N4O6/c33-23-9-5-21(19-25(23)35)7-11-27(37)31-17-3-15-29-13-1-2-14-30-16-4-18-32-28(38)12-8-22-6-10-24(34)26(36)20-22/h5-6,9-10,19-20,29-30,33-36H,1-4,7-8,11-18H2,(H,31,37)(H,32,38)
InChIKey: IOLDDENZPBFBHV-UHFFFAOYSA-N
- Boiling Point: 872.1±65.0 °C (Predicted)
- Appearance: Off-white to Yellow Solid
- Storage: Store at -20 °C
Synonyms:
N1,N2-bis(dihydrocaffeoyl)spermine; 1,14-Bis(dihydrocaffeoyl)spermidine; N,N'-[1,4-butanediylbis(imino-3,1-propanediyl)]bis[3,4-dihydroxy-benzenepropanamide]
More details are to be found on supplier website
