Germany
BuGuCh & Partners
Synonyms: 4-methyl-benzenesulfonamid;4-Toluenesulfanamide;Benzenesulfonamide, 4-methyl-;Benzenesulfonamide,4-methyl-;para-toluenesulfamine;para-Toluenesulfonamide;p-Methylbenzenesulfonamide;p-Toluenesulfamide
CAS: 70-55-3
MF: C7H9NO2S
MW: 171.22
EINECS: 200-741-1
Mol File: 70-55-3.mol
p-Toluenesulfonamide Chemical Properties
Melting point 134-137 °C(lit.)
Boiling point 221 °C (10 mmHg)
Fp 202 °C
Water Solubility 0.32 g/100 mL (25 º C)
BRN 472689
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36-20/21/22
Safety Statements 26-36
WGK Germany 1
RTECS XT5075000
PackingGroup III
HS Code 29350090
Chemical Properties It is white flaky crystal. It is soluble in ethanol but insoluble in water and ether.
Uses
1. It is used in the manufacture of dyes, synthetic resins, paints, disinfectants and wood processing brightener.
2. It is used for the manufacture of plasticizers, disinfectants; it can also be used for the production of synthetic resins, paints, and fluorescent dyes.
3. It can be used as primary brightener in the bright nickel plating. It is sued for bright nickel plating for multilayer to obtain uniform bright coating. It has a commonly used amount of 0.2 ~ 0.3 g / L.
4. It can be used as plasticizers, also used for synthesis of organics, resins and saccharin.
Production methods It is obtained by the reaction between toluenesulfonyl chloride and ammonia.
First, add part of HN3 water into the reaction pot, stirring for adding p-toluenesulfonyl chloride with the temperature rising naturally to above 50 °C; after the temperature has dropped, add the remaining ammonia and have reaction for 0.5 h at 85 ~ 90 °C. Stop the reaction when the pH reaches 8 to 9. Cool to 20 °C, filter, and wash the filter cake with water to obtain the crude. Then further go through bleaching via activated carbon, alkali dissolution, acid precipitation, rejection filter, drying to get products.
Chemical Properties white crystalline powder
Usage 4-Tolylsulfonamide is a carbonic anhydrase inhibitor used the synthesis of antiglaucoma and anticancer drugs.
Usage Used in the manufacture of plasticizer, disinfectant, fungicide, fungicides, wood brightener.
Also can be used in the production of synthetic resin, the coating, the fluorescent dye, pharmaceutical, etc.
