Description:
Sapropterin is a naturally occurring cofactor for phenylalanine hydroxylase. Under the trade name Kuvan, sapropterin dihydrochloride is approved for the treatment of hyperphenylalaninaemia and tetrahydrobiopterin deficiency.
- Molecular Weight: 314.17
- Molecular Formula: C9H17Cl2N5O3
Purity: >98%
Canonical SMILES:
CC(C(C1CNC2=C(N1)C(=O)NC(=N2)N)O)O.Cl.Cl
InChI:
InChI=1S/C9H15N5O3.2ClH/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7;;/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17);2*1H/t3-,4+,6-;;/m0../s1
InChIKey: RKSUYBCOVNCALL-NTVURLEBSA-N
- Melting Point: >202°C (dec.)
- Solubility: Soluble in Aqueous Acid (Slightly), DMSO (Slightly), Water (Slightly)
- Appearance: White to Off-white Solid
- Storage: Store at -20°C
Synonyms:
BioMarin T 1401; Biopten; Kuvan; SUN 0588; Shiratori SN 0588; (6R)-5,6,7,8-Tetrahydrobiopterin Dihydrochloride; Phenoptin; (R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(3H)-one dihydrochloride; (6R)-Tetrahydrobiopterin hydrochloride; (6R)-5,6,7,8-Tetrahydro-L-Biopterin Dihydrochloride
More details are to be found on supplier website
