Description:
GW4869 is a cell-permeable, specific and non-competitive inhibitor of neutral sphingomyelinases (IC50 = 1 μM).
- Molecular Weight: 577.5
- Molecular Formula: C30H30Cl2N6O2
Canonical SMILES:
C1CN=C(N1)C2=CC=C(C=C2)NC(=O)C=CC3=CC=C(C=C3)C=CC(=O)NC4=CC=C(C=C4)C5=NCCN5.Cl.Cl
InChI:
1S/C30H28N6O2.2ClH/c37-27(35-25-11-7-23(8-12-25)29-31-17-18-32-29)15-5-21-1-2-22(4-3-21)6-16-28(38)36-26-13-9-24(10-14-26)30-33-19-20-34-30;;/h1-16H,17-20H2,(H,31,32)(H,33,34)(H,35,37)(H,36,38);2*1H/b15-5+,16-6+;;
InChIKey: NSFKAZDTKIKLKT-CLEIDKRQSA-N- Solubility: DMSO: 0.044 mg/mL (Need ultrasonic and warming)
- Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms:
(E)-3-[4-[(E)-3-[4-(4,5-dihydro-1H-imidazol-2-yl)anilino]-3-oxoprop-1-enyl]phenyl]-N-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]prop-2-enamide;dihydrochloride; GW 4869; GW-4869
More details are to be found on supplier website
