Description:
Bestatin hydrochloride is a competitive aminopeptidase inhibitor, which is studied for use in the treatment of acute myelocytic leukemia. It has become a useful tool in elucidating the physiological role of some mammalian exopeptidases in the regulation of the immune system, in the growth of tumors and their invasion of surrounding tissues, and in the degradation of cellular proteins.
- Molecular Weight: 344.83
- Molecular Formula: C16H24N2O4.HCl
Purity: >98%
Canonical SMILES:
CC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O.Cl
InChI:
InChI=1S/C16H24N2O4.ClH/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11; /h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22); 1H/t12-,13+,14+; /m1./s1
InChIKey: XGDFITZJGKUSDK-UDYGKFQRSA-N
- Boiling Point: 604.7°C at 760 mmHg
- Melting Point: 216-218°C
- Solubility: Soluble in DMSO
- Appearance: White to Off-white Powder
- Storage: Store at -20°C
Synonyms:
Aminopeptidase inhibitor; leucine aminopeptidase; aminopeptidase B; NK-421
More details are to be found on supplier website
