Description:
MTDIA is a human 5'-methylthioadenosine phosphorylase (MTAP) inhibitor, which is solely responsible for 5'-methylthioadenosine (MTA) metabolism to permit S-adenosylmethionine salvage. It is used as an anticancer candidate.
- Molecular Weight: 294.35
- Molecular Formula: C13H19N5OS
Purity: 98%
Canonical SMILES:
CSCC1CN(CC1O)CC2=CNC3=C2N=CN=C3N
InChI:
InChI=1S/C13H19N5OS/c1-20-6-9-4-18(5-10(9)19)3-8-2-15-12-11(8)16-7-17-13(12)14/h2,7,9-10,15,19H,3-6H2,1H3,(H2,14,16,17)/t9-,10+/m1/s1
InChIKey: NTHMDFGHOCNNOE-ZJUUUORDSA-N
- Boiling Point: 566.1±50.0 °C | Condition: Press: 760 Torr
- Melting Point: 108-110 °C
- Solubility: Soluble in DMSO, not in water
- Appearance: Solid powder
- Storage: -20°C Freezer
Synonyms:
Methylthio-DADMe-Immucillin A; MT-DADMe-ImmA; (3R,4S)-1-((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-3-hydroxy-4-((methylthio)methyl)pyrrolidin-1-ium
More details are to be found on supplier website
