Description:
GIT 27 is an orally active immunomodulatory agent. It inhibits TNF-α secretion via interference of macrophage TLR4 and TLR 2/6 signaling pathway.
- Molecular Weight: 205.21
- Molecular Formula: C11H11NO3
Canonical SMILES:
C1C(ON=C1C2=CC=CC=C2)CC(=O)O
InChI:
1S/C11H11NO3/c13-11(14)7-9-6-10(12-15-9)8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,13,14)
InChIKey: MUFJHYRCIHHATF-UHFFFAOYSA-N- Boiling Point: 381.44 °C at 760 mmHg (Predicted)
- Melting Point: 132.14 °C (Predicted)
- Solubility: Soluble to 100 mM in DMSO
- Appearance: White to Off-White Solid
- Storage: Store at +4°C
Synonyms:
5-Dihydro-3-phenyl-5-isoxazoleacetic acid; (S,R)-3-Phenyl-4,5-dihydro-5-isoxazole acetic acid; 3-phenyl-4,5-dihydro-5-isoxazole acetic acid; VGX-1027; VGX 1027; VGX1027; GIT 27; GIT-27; GIT27
More details are to be found on supplier website
