Description:
AS-604850 is a selective, ATP-competitive PI3Kγ inhibitor with IC50 of 250 nM, over 80-fold selectivity for PI3Kγ than PI3Kδ/β, and 18-fold more selective for PI3Kγ than PI3Kα.
- Molecular Weight: 285.211
- Molecular Formula: C11H5F2NO4S
Purity: 98%
Canonical SMILES:
C1=CC2=C(C=C1C=C3C(=O)NC(=O)S3)OC(O2)(F)F
InChI:
InChI=1S/C11H5F2NO4S/c12-11(13)17-6-2-1-5(3-7(6)18-11)4-8-9(15)14-10(16)19-8/h1-4H,(H,14,15,16)/b8-4+
InChIKey: SRLVNYDXMUGOFI-XBXARRHUSA-N
Synonyms:
AS604850; AS 604850; AS-604850. PI3K gamma inhibitor; PI 3-Kgamma Inhibitor II; (5E)-5-[(2,2-Difluoro-1,3-benzodioxol-5-YL)methylene]-1,3-thiazolidine-2,4-dione
More details are to be found on supplier website
