Description:
SD-208 is a selective TGF-βRI (ALK5) inhibitor with IC50 of 48 nM, >100-fold selectivity over TGF-βRII.
- Molecular Weight: 352.75
- Molecular Formula: C17H10ClFN6
Purity: >98%
Canonical SMILES:
C1=CC(=C(C=C1Cl)C2=NC3=NC=CN=C3C(=N2)NC4=CC=NC=C4)F
InChI:
InChI=1S/C17H10ClFN6/c18-10-1-2-13(19)12(9-10)15-24-16-14(21-7-8-22-16)17(25-15)23-11-3-5-20-6-4-11/h1-9H,(H,20,22,23,24,25)
InChIKey: BERLXWPRSBJFHO-UHFFFAOYSA-N
Synonyms:
SD-208; SD 208; SD208; TGF-β RI Kinase Inhibitor V.
More details are to be found on supplier website