Description:
Tertiapin is a 21-amino acid peptide isolated from the venom of the honey bee (Apis mellifera). It was shown to block inward rectifier potassium channels (Kir) and calcium activated large conductance potassium channels (BK).
- Molecular Weight: 2459.14
- Molecular Formula: C106H180N34O23S5
Purity: ≥95% by HPLC
Canonical SMILES:
O=C(N)CC(NC(=O)C(NC(=O)C(NC(=O)C(N)C)CC(C)C)CS)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N)CCCCN)CCCCN)CS)CCCCN)CCCCN)CC2=CNC=3C=CC=CC32)CS)CCSC)CC4=CN=CN4)C(C)CC)C(C)CC)C(C)CC)CCCNC(=N)N)CC(=O)N)CS
InChI:
InChI=1S/C106H180N34O23S5/c1-11-56(6)83(137-93(151)68(32-24-39-118-106(115)116)126-97(155)73(45-80(112)141)130-101(159)78(53-167)136-98(156)74(46-81(113)142)131-100(158)77(52-166)135-94(152)70(42-55(4)5)128-87(145)59(9)111)103(161)138-84(57(7)12-2)104(162)139-85(58(8)13-3)105(163)140-40-25-33-79(140)102(160)132-72(44-61-48-117-54-121-61)96(154)127-69(34-41-168-10)92(150)134-76(51-165)99(157)129-71(43-60-47-119-63-27-15-14-26-62(60)63)95(153)125-66(30-18-22-37-109)90(148)124-67(31-19-23-38-110)91(149)133-75(50-164)88(146)120-49-82(143)122-65(29-17-21-36-108)89(147)123-64(86(114)144)28-16-20-35-107/h14-15,26-27,47-48,54-59,64-79,83-85,119,164-167H,11-13,16-25,28-46,49-53,107-111H2,1-10H3,(H2,112,141)(H2,113,142)(H2,114,144)(H,117,121)(H,120,146)(H,122,143)(H,123,147)(H,124,148)(H,125,153)(H,126,155)(H,127,154)(H,128,145)(H,129,157)(H,130,159)(H,131,158)(H,132,160)(H,133,149)(H,134,150)(H,135,152)(H,136,156)(H,137,151)(H,138,161)(H,139,162)(H4,115,116,118)/t56-,57-,58-,59-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,83-,84-,85-/m0/s1
InChIKey: YUJSAJLRLLRZPV-YJOCJKAQSA-N
- Solubility: Soluble in Water
- Appearance: White Lyophilized Powder
- Storage: Store at -20°C
Synonyms:
H-Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Met-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2; L-Alanyl-L-leucyl-L-cysteinyl-L-asparaginyl-L-cysteinyl-L-asparaginyl-L-arginyl-L-isoleucyl-L-isoleucyl-L-isoleucyl-L-prolyl-L-histidyl-L-methionyl-L-cysteinyl-L-tryptophyl-L-lysyl-L-lysyl-L-cysteinylglycyl-L-lysyl-L-lysinamide; Tertiapin (reduced)
More details are to be found on supplier website
