Description:
Maytansinol is an ansamacrolide isolated from P. verrucose. It was shown to inhibit microtubule assembly and induces microtubule disassembly in vitro. It exhibits antitumor activity.
- Molecular Weight: 565.06
- Molecular Formula: C28H37ClN2O8
Purity: 95%
Canonical SMILES:
CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)O)C)C)OC)(NC(=O)O2)O
InChI:
InChI=1S/C28H37ClN2O8/c1-15-8-7-9-22(37-6)28(35)14-20(38-26(34)30-28)16(2)25-27(3,39-25)21(32)13-23(33)31(4)18-11-17(10-15)12-19(36-5)24(18)29/h7-9,11-12,16,20-22,25,32,35H,10,13-14H2,1-6H3,(H,30,34)/b9-7+,15-8+/t16-,20+,21+,22-,25+,27+,28+/m1/s1
InChIKey: QWPXBEHQFHACTK-RZKXNLMUSA-N
- Boiling Point: 835.8±65.0 °C at 760 mmHg
- Melting Point: 205-207°C
- Solubility: Soluble in Chloroform (Slightly), Methanol (Slightly)
- Appearance: Off-white to Orange Solid
- Storage: Store at -20°C under inert atmosphere
Synonyms:
(3S)-3-O-De[2-(acetylmethylamino)-1-oxopropyl]-maytansine; Ansamitocin P-0; NSC239386; NSC-239386; Maytansine; Ansamitocin P 0; Antibiotic C 15003P; NSC 239386
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