Description:
A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
- Molecular Weight: 358.44
- Molecular Formula: C22H22N4O
Purity: >98%
Canonical SMILES:
CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OCC(CC4=CC=CC=C4)N
InChI:
InChI=1S/C22H22N4O/c1-15-21-11-17(7-8-22(21)26-25-15)18-10-20(13-24-12-18)27-14-19(23)9-16-5-3-2-4-6-16/h2-8,10-13,19H,9,14,23H2,1H3,(H,25,26)/t19-/m0/s1
InChIKey: BPNUQXPIQBZCMR-IBGZPJMESA-N
- Boiling Point: 624.4±55.0°C at 760 mmHg
- Solubility: Soluble in DMSO (72 mg/mL at 25°C), Ethanol (18 mg/mL at 25°C), Water (72 mg/mL at 25°C)
- Appearance: Crystalline Solid
- Storage: Store at -20°C
Synonyms:
A674563; A 674563; Benzeneethanamine, α-[[[5-(3-methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]-, (αS)-; (αS)-α-[[[5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]benzeneethanamine; (S)-1-((5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl)oxy)-3-phenylpropan-2-amine
More details are to be found on supplier website
