Description:
Euscaphic acid is isolated from the dried fruit of Ziziphus jujuba. It inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of IKK and MAPKs signal transduction to downregulate NF-κB activations.
- Molecular Weight: 488.7
- Molecular Formula: C30H48O5
Purity: 98%
Canonical SMILES:
CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C)O)O)C)C)C2C1(C)O)C)C(=O)O
InChI:
InChI=1S/C30H48O5/c1-17-10-13-30(24(33)34)15-14-27(5)18(22(30)29(17,7)35)8-9-21-26(4)16-19(31)23(32)25(2,3)20(26)11-12-28(21,27)6/h8,17,19-23,31-32,35H,9-16H2,1-7H3,(H,33,34)/t17-,19-,20+,21-,22-,23-,26+,27-,28-,29-,30+/m1/s1
InChIKey: OXVUXGFZHDKYLS-QUFHAEKXSA-N
- Boiling Point: 602.7±55.0 °C at 760 mmHg
- Melting Point: 262-264 °C(Solv: chloroform (67-66-3); methanol (67-56-1))
- Solubility: methanol (Slightly), Pyridine (Slightly)
- Appearance: Powder
- Application: antifungal; anti-diabetic activity; anti-inflammatory
- Storage: -20°C Freezer
Synonyms:
Acuminatic acid
More details are to be found on supplier website