Description:
N4-benzoyl-5'-O-tert-Butyldimethylsilyl-2'-deoxycytidine, a potent antitumor agent, offers therapy for an array of cancers like metastatic breast cancer, non-small cell lung cancer, pancreatic cancer, and bladder cancer. Its mechanism of action involves inhibiting DNA synthesis by interrupting the replication of DNA strands. By integrating itself into these strands, it results in premature chain termination. The compound thus offers a promising avenue for cancer therapy.
- Molecular Weight: 445.58
- Molecular Formula: C22H31N3O5Si
Purity: ≥97% by HPLC
Canonical SMILES:
CC(C)(C)[Si](C)(C)OCC1C(CC(O1)N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)O
InChI:
InChI=1S/C22H31N3O5Si/c1-22(2,3)31(4,5)29-14-17-16(26)13-19(30-17)25-12-11-18(24-21(25)28)23-20(27)15-9-7-6-8-10-15/h6-12,16-17,19,26H,13-14H2,1-5H3,(H,23,24,27,28)/t16-,17+,19+/m0/s1
InChIKey: CCPOWNJNXQQIFV-YQVWRLOYSA-N
Synonyms:
5'-O-TBDMS-N4-Bz-dc; 5'-O-TBDMS-N4-Benzoyl-2'-deoxycytidine; N-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxycytidine; N-Bz-5'-O-TBS dC; Cytidine, N-benzoyl-2'-deoxy-5'-O-[(1,1-dimethylethyl)dimethylsilyl]-; N-Benzoyl-2'-deoxy-5'-O-[dimethyl(2-methyl-2-propanyl)silyl]cytidine
More details are to be found on supplier website
