Description:
Luteolin is an anti-inflammatory, antioxidant and free radical scavenger. Luteolin inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 activation. It also inhibits TNF-α-induced COX-2 expression, and phosphodiesterase with with Ki of 15.0 μM, 6.4 μM, 13.9 μM, 11.1 μM and 9.5 μM for PDE1-5 respectively. It inhibits proliferation of Lewis lung carcinoma cells in vivo. Luteolin is a natural compound found in the leaves of Dracocephalum ruyschiana L. It can be used in cosmetics material.
- Molecular Weight: 286.24
- Molecular Formula: C15H10O6
Purity: ≥98% (TLC)
Canonical SMILES:
C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O
InChI:
InChI=1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H
InChIKey: IQPNAANSBPBGFQ-UHFFFAOYSA-N
- Boiling Point: 616.00to617.00°C.at760.00mmHg(est)
- Melting Point: 328-330 °C
- Solubility: Soluble in aqueous alkaline solutions
- Appearance: Yellow solid
- Application: ADCs Cytotoxin
- Storage: In a dry, cool place
Synonyms:
3',4',5,7-Tetrahydroxyflavone; Digitoflavone; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one; Flacitran
More details are to be found on supplier website
