Description:
Osthole is a coumarin which is isolated from Cnidium monnieri (L.) Cusson. Osthole is a calcium channel modulator via inhibiting phosphodiesterases. It also regulates the expression of TNF-α, NF-κB, TGF-β, cyclooxygenases, leukotrienes, nitric oxide, ERK, and JNK. Osthole is a natural compound used in cosmetics material.
- Molecular Weight: 244.29
- Molecular Formula: C15H16O3
Purity: ≥ 98%
Canonical SMILES:
CC(=CCC1=C(C=CC2=C1OC(=O)C=C2)OC)C
InChI:
InChI=1S/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3
InChIKey: MBRLOUHOWLUMFF-UHFFFAOYSA-N
- Boiling Point: 396.7±42.0 °C at 760 mmHg
- Melting Point: 83-84°C
- Solubility: In vitro: 10 mM in DMSO
- Appearance: Cryst.
- Application: anti-tumor; anti-cancer; may be used as bio-pesticides
- Storage: Powder: -20°C: 3 years4°C: 2 yearsIn solvent: -80°C: 6 months-20°C: 1 month
Synonyms:
Osthol; 7-methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one
More details are to be found on supplier website
