Description:
Theaflavin is an antioxidant polyphenol which is formed from the condensation of flavan-3-ols in tea leaves during the enzymatic oxidation (fermentation) of black tea. It can inhibit HIV-1 replication with multiple mechanisms of action, and tumor necrosis factor-alpha mediated Interleukin-8 gene expression. It exhibits differential inhibitory effects on cancer cell lines and has the potential to be used individually for functional food applications and for therapy targeting specific cancer treatment.Nutritional supplement in health care products.
- Molecular Weight: 564.499
- Molecular Formula: C29H24O12
Purity: >98%
Canonical SMILES:
C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC4=C(C(=C(C=C4C5C(CC6=C(C=C(C=C6O5)O)O)O)O)O)C(=O)C(=C3)O)O
InChI:
InChI=1S/C29H24O12/c30-11-3-17(32)15-8-21(36)28(40-23(15)5-11)10-1-13-14(7-20(35)27(39)25(13)26(38)19(34)2-10)29-22(37)9-16-18(33)4-12(31)6-24(16)41-29/h1-7,21-22,28-33,35-37,39H,8-9H2,(H,34,38)/t21-,22-,28-,29-/m1/s1
InChIKey: IPMYMEWFZKHGAX-ZKSIBHASSA-N
- Boiling Point: 926.2±65.0 °C at 760 mmHg
- Melting Point: 240 °C
- Solubility: In Vitro: H2O : 2 mg/mL (3.54 mM; Need ultrasonic and warming)DMSO : 1.42 mg/mL (2.52 mM; Need ultrasonic and warming)
- Appearance: Powder
- Application: Ingredient of health care products.
- Storage: Powder: -20°C: 3 years4°C: 2 yearsIn solvent: -80°C: 6 months-20°C: 1 month
Synonyms:
1,8-Bis(3-alpha,5,7-trihydroxy-2-alpha-chromanyl)-5h-benzocyclohepten-5-one; 5H-benzocyclohepten-5-one,1,8-bis(3-alpha,5,7-trihydroxy-2-alpha-chromanyl)-3; 6,8,9-trihydroxy-3,11-bis[(2S,3R)-3,5,7-trihydroxychroman-2-yl]bicyclo[5.4.0]undeca-1,3,6,8,10-pentaen-5-one; 3,4,5-Trihydroxy-1,8-bis[(2R,3R)-3,5,7-trihydroxy-2-chromanyl]-6-benzo[7]annulenone; 3,4,6-Trihydroxy-1,8-bis(3α,5,7-trihydroxy-2α-chromanyl)-5H-benzocyclohepten-5-one
More details are to be found on supplier website
