Description:
PS-1145 is a selective IκB kinase (IKK) inhibitor (IC50 = 100 nM). PS1145 efficiently inhibited both basal and induced NF-kappaB activity in PC cells.
- Molecular Weight: 322.75
- Molecular Formula: C17H11ClN4O
Purity: 98%
Canonical SMILES:
O=C(C1=CC=CN=C1)NC2=CC(Cl)=CC3=C2NC4=C3C=CN=C4
InChI:
InChI=1S/C17H11ClN4O/c18-11-6-13-12-3-5-20-9-15(12)21-16(13)14(7-11)22-17(23)10-2-1-4-19-8-10/h1-9,21H,(H,22,23)
InChIKey: JZRMBDHPALEPDM-UHFFFAOYSA-N
- Solubility: Soluble in DMSO, not in water
- Appearance: Yellow solid powder
- Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Synonyms:
N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)nicotinamide; PS-1145; PS 1145; PS1145
More details are to be found on supplier website
