Description:
Belinostat is a hydroxamic acid-type histone deacetylase (HDAC) inhibitor. Belinostat targets HDAC enzymes to inhibit tumor cell proliferation and angiogenesis, induce apoptosis and promote cellular differentiation.
- Molecular Weight: 318.347
- Molecular Formula: C15H14N2O4S
Canonical SMILES:
C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)C=CC(=O)NO
InChI:
InChI=1S/C15H14N2O4S/c18-15(16-19)10-9-12-5-4-8-14(11-12)22(20,21)17-13-6-2-1-3-7-13/h1-11,17,19H,(H,16,18)/b10-9+
InChIKey: NCNRHFGMJRPRSK-MDZDMXLPSA-N- Melting Point: 142 - 145°C
- Appearance: Off-White to Pale Orange Solid
- Application: Antineoplastic Agents
Synonyms:
Belinostat; PXD 101; Beleodaq; PDX101; PX 105684; PXD-101; PXD101; (E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide
More details are to be found on supplier website
