Description:
DOPE, also known as 1,2-Dioleoyl-sn-glycero-3-PE or 1,2-DOPE, is a synthetic analog of naturally-occurring PE containing 18: 1 fatty acids at the sn-1 and sn-2 positions. 1,2-DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes. It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.
- Molecular Weight: 744.1
- Molecular Formula: C41H78NO8P
Purity: 0.95
Canonical SMILES:
CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)OCCN)OC(=O)CCCCCCCC=CCCCCCCCC
InChI:
InChI=1S/C41H78NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,39H,3-16,21-38,42H2,1-2H3,(H,45,46)/b19-17-,20-18-/t39-/m1/s1
InChIKey: MWRBNPKJOOWZPW-NYVOMTAGSA-N
- Boiling Point: 759.22°C at 760 mmHg
- Melting Point: 200 °C
- Solubility: Chloroform: 3.3 mg/ml
- Appearance: Freeze-dried Powder
- Storage: -20°C
Synonyms:
18: 1 PE; 1,2-Dioleoyl-sn-glycero-3-PE; 1,2-Dioleoyl-sn-glycero-3-Phosphoethanolamine; 1,2-DOPE
More details are to be found on supplier website
