Description:
Reagent for the quantitative reduction of disulfide group. Prevents the oxidation of cholecystokinin during its extraction from brain and duodenal tissues. Cleavage of disulfide bonds in proteins.
- Molecular Weight: 154.25
- Molecular Formula: C4H10O2S2
Purity: ≥ 99 % (Assay by titration)
Canonical SMILES:
C(C(C(CS)O)O)S
InChI:
InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1
InChIKey: VHJLVAABSRFDPM-QWWZWVQMSA-N
- Boiling Point: 125.0-130.0 °C at 2 mmHg
- Melting Point: 41-44 °C
- Solubility: Soluble in Water (50 mg/mL, clear, colorless)
- Appearance: White crystals or free flowing powder
- Application: Used as a reagent in biochemistry to prevent oxidation of thiol groups and to reduce disulfides to dithiols; Has been used as a radioprotectant; Dithiothreitol (DTT) is the common name for a small-molecule redox reagent known as Cleland's reagent.
- Storage: Store at 2-8 °C
Synonyms:
DL-1,4-Dithiothreitol; DTT; Cleland's reagent; threo-1,4-Dimercapto-2,3-butanediol; Dithiothreitol; dl-Dithiothreitol; 1,4-Dithiothreitol; D-Dtt; 1,4-Dithio-dl-threitol; DL-Dithiothreitol; threo-1,4-Dimercapto-2,3-butanediol
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