Description:
EIDD-1931 is a ribonucleoside analog that exhibits potential antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV. EIDD-1931 induces mutations in RNA virions, inhibiting SARS-CoV-2 and other coronavirus in mice and human airway epithelial cells.
- Molecular Weight: 259.22
- Molecular Formula: C9H13N3O6
Purity: 99.73%
Canonical SMILES:
C1=CN(C(=O)N=C1NO)C2C(C(C(O2)CO)O)O
InChI:
InChI=1S/C9H13N3O6/c13-3-4-6(14)7(15)8(18-4)12-2-1-5(11-17)10-9(12)16/h1-2,4,6-8,13-15,17H,3H2,(H,10,11,16)/t4-,6-,7-,8-/m1/s1
InChIKey: XCUAIINAJCDIPM-XVFCMESISA-N
- Solubility: In Vitro: DMSO : 100 mg/mL(385.77 mM;Need ultrasonic)In Vivo: 1.Add each solvent one by one: 10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% salineSolubility: ≥ 2.08 mg/mL (8.02 mM); Clear solution2.Add each solvent one by one: 10% DMSO >> 90% (20%SBE-β-CDin saline)Solubility: ≥ 2.08 mg/mL (8.02 mM); Clear solution3.Add each solvent one by one: 10% DMSO >> 90%corn oilSolubility: ≥ 2.08 mg/mL (8.02 mM); Clear solution
- Appearance: White to off-white (Solid)
- Storage: Powder: -20°C: 3 years4°C: 2 years* The compound is unstable in solutions, freshly prepared is recommended.
Synonyms:
N4-Hydroxycytidine; N(4)-Hydroxycytidine; Uridine, 4-oxime; Beta-D-N4-hydroxycytidine
More details are to be found on supplier website
