Description:
Biotinoyl tripeptide-1 is a peptide beneficial for hair conditioning. Biotinoyl tripeptide-1 is also used in anti-aging cosmetics. Biotinoyl tripeptide-1 is a tripeptide that combines vitamin H with the Matrikine series GHK. Biotinoyl tripeptide-1 can stimulate the synthesis of collagen IV and laminin 5, and fix hair in the dermal hair follicle to prevent hair loss.
- Molecular Weight: 566.67
- Molecular Formula: C24H38N8O6S
Purity: >95%
Canonical SMILES:
C1C2C(C(S1)CCCCC(=O)NCC(=O)NC(CC3=CN=CN3)C(=O)NC(CCCCN)C(=O)O)NC(=O)N2
InChI:
InChI=1S/C24H38N8O6S/c25-8-4-3-5-15(23(36)37)30-22(35)16(9-14-10-26-13-28-14)29-20(34)11-27-19(33)7-2-1-6-18-21-17(12-39-18)31-24(38)32-21/h10,13,15-18,21H,1-9,11-12,25H2,(H,26,28)(H,27,33)(H,29,34)(H,30,35)(H,36,37)(H2,31,32,38)/t15-,16-,17-,18-,21-/m0/s1
InChIKey: WCKVVODUWGBPQV-SOADLSRISA-N
- Boiling Point: 1128.5±65.0°C(Predicted)
- Solubility: Soluble in DMSO
- Appearance: Solid
- Application: Biotinylated tripeptide-1, also known as vitamin H peptide, plays a vital role in drug discovery due to its unique properties and potential therapeutic applications. This peptide is composed of biotin, a water-soluble B vitamin that is essential for various biochemical processes, and a tripeptide composed of three amino acids. In drug discovery, biotinylated tripeptide-1 has received attention for its ability to promote hair growth, enhance cell proliferation, and stimulate tissue repair mechanisms.The application of biotinylated tripeptide-1 in drug discovery is mainly focused on dermatology and regenerative medicine. Studies have shown that this peptide can stimulate hair follicle growth and improve hair thickness and density, making it a promising candidate for the treatment of hair loss diseases such as alopecia. By promoting dermal papilla cell proliferation and increasing keratinocyte production, biotinylated tripeptide-1 can help restore the hair growth cycle and improve hair quality.In addition, biotinylated tripeptide-1 has been studied for its potential in wound healing and tissue regeneration. This peptide can accelerate the healing process by promoting collagen synthesis, enhancing fibroblast proliferation, and stimulating angiogenesis. These mechanisms help speed up tissue repair and regeneration, making Biotipeptide-1 a valuable component in the development of advanced wound care products and regenerative therapies.Applications of Biotipeptide-1 in drug discovery are not just restricted to regenerative medicine and dermatology. Its potential is being investigated by researchers in a number of therapeutic domains, such as neurology, cancer, and metabolic disorders. According to studies, this peptide may improve synaptic plasticity and support neuronal survival, both of which may have neuroprotective effects. Biotipeptide-1 has demonstrated antiproliferative qualities against cancer cells in oncology, indicating its potential as an adjuvant treatment for specific cancer types. This peptide has also been studied for its potential to alter insulin sensitivity and adipocyte function in metabolic diseases like diabetes and obesity.Because of its special qualities, Biotipeptide-1 is a desirable candidate for therapeutic development and discovery. Its effectiveness and adaptability in a range of therapeutic applications are attributed to its tiny molecular size, water solubility, and bioavailability. This peptide has positive impacts on cellular function and tissue regeneration through altering important cellular pathways and signaling mechanisms, opening up new treatment options for complex disorders.In drug discovery, researchers employ various techniques to study the pharmacokinetics, pharmacodynamics, and safety of biotin tripeptide-1. Preclinical studies involve in vitro and in vivo experiments to evaluate the peptide's biological activity, mechanism of action, and toxicity profile. These studies provide valuable insights into the therapeutic potential of biotin tripeptide-1 and guide the further development of drug candidates based on this peptide.In addition, researchers utilize advanced drug delivery systems to improve the bioavailability and targeted delivery of biotin tripeptide-1. Nanoparticles, liposomes, and micelles are among the various nanoformulations used to encapsulate and protect peptides, which can improve their stability and efficacy in vivo. These drug delivery systems enable precise control of the release kinetics of biotin tripeptide-1, ensuring optimal therapeutic effects and minimizing potential side effects.
- Storage: Store at -20°C
Synonyms:
Biotin tripeptide-1; N-[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]glycyl-L-histidyl-L-lysine; Biotin tripeptide 1; Biotin-GHK; Biotinoyl Tripeptide 1; Biotinoylglycylhistidyllysine; Biotinyl-GHK tripeptide
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