Description:
T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively. T0901317 induces apoptosis and inhibits the development of atherosclerosis in low-density lipoprotein (LDL) receptor-deficient mice.
- Molecular Weight: 481.33
- Molecular Formula: C17H12F9NO3S
Purity: >98%
Canonical SMILES:
C1=CC=C(C=C1)S(=O)(=O)N(CC(F)(F)F)C2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O
InChI:
InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2
InChIKey: SGIWFELWJPNFDH-UHFFFAOYSA-N
- Boiling Point: 470.55°C at 760 mmHg
- Melting Point: 116-122°C
- Storage: Store at -20°C
Synonyms:
T 0901317; T-0901317; TO-901317; TO901317; N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzenesulfonamide; T-1317
More details are to be found on supplier website
