Description:
Sorafenib is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively.
- Molecular Weight: 464.82
- Molecular Formula: C21H16ClF3N4O3
Purity: >98%
Canonical SMILES:
CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F
InChI:
InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)
InChIKey: MLDQJTXFUGDVEO-UHFFFAOYSA-N
- Melting Point: 202-206°C
- Appearance: Off-White to Light Yellow Solid
Synonyms:
BAY 43-9006
More details are to be found on supplier website
