Description:
Crebanine is isolated from the herbs of Stephania yunnanensis. Crebanine might be used as the starting point to develop a drug for Alzheimer's disease, having potential utility of crebanine in the development of neurodegenerative therapy. Inhibiting the proliferation of human leukemic cells (HL-60, U937 and K562), human fibrosarcoma cells (HT1080) and cervix cancer cell lines (KB-3-1 and KB-V1), Crebanine has anti-cancer activity.
- Molecular Weight: 339.4
- Molecular Formula: C20H21NO4
Purity: 97%
Canonical SMILES:
CN1CCC2=CC3=C(C4=C2C1CC5=C4C=CC(=C5OC)OC)OCO3
InChI:
InChI=1S/C20H21NO4/c1-21-7-6-11-8-16-20(25-10-24-16)18-12-4-5-15(22-2)19(23-3)13(12)9-14(21)17(11)18/h4-5,8,14H,6-7,9-10H2,1-3H3
InChIKey: UVDQDNQWGQFIAO-UHFFFAOYSA-N
- Boiling Point: 488.2±45.0°C (Predicted)
- Melting Point: 126°C
- Appearance: Cryst.
- Application: antiarrhythmic; anti-tumor; anti-cancer
Synonyms:
Crebanin; 8,9-Dimethoxy-1,2-methylenedioxyaporphine
More details are to be found on supplier website
