Description:
Palbociclib Impurity 2 is an impurity of Palbociclib, which is a selective cyclin-dependent kinases CDK4 and CDK6 inhibitor used for the treatment of ER-positive and HER2-negative breast cancer.
- Molecular Weight: 431.53
- Molecular Formula: C24H29N7O
Purity: 95%
Canonical SMILES:
CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C=C
InChI:
InChI=1S/C24H29N7O/c1-3-19-16(2)20-15-27-24(29-22(20)31(23(19)32)17-6-4-5-7-17)28-21-9-8-18(14-26-21)30-12-10-25-11-13-30/h3,8-9,14-15,17,25H,1,4-7,10-13H2,2H3,(H,26,27,28,29)
InChIKey: BAMRZESJXFABIT-UHFFFAOYSA-N
- Boiling Point: 672.3±65.0°C at 760 mmHg
- Melting Point: >163°C (dec.)
- Solubility: Soluble in DMSO (Very Slightly, Heated)
- Appearance: Light Yellow Solid
- Storage: Store at -20°C under inert atmosphere
Synonyms:
Desoxo-palbociclib; Pyrido[2,3-d]pyrimidin-7(8H)-one, 8-cyclopentyl-6-ethenyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-; 8-Cyclopentyl-6-ethenyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one; Palbociclib Impurity D
More details are to be found on supplier website
