Description:
Dendrobine, that can be found in the herb of Dendrobium nobile Lindl, produces moderate hyperglycemia, diminishes cardiac activity in large doses, lowers the blood pressure. Dendrobine on the electrical activity and on amino acid-induced depolarizations of primary afferent terminals were tested on the frog isolated spinal cord.
- Molecular Weight: 263.38
- Molecular Formula: C16H25NO2
Purity: >98%
Canonical SMILES:
CC(C)C1C2C3CCC4C3(C(C1OC2=O)N(C4)C)C
InChI:
InChI=1S/C16H25NO2/c1-8(2)11-12-10-6-5-9-7-17(4)14(16(9,10)3)13(11)19-15(12)18/h8-14H,5-7H2,1-4H3/t9-,10+,11+,12-,13-,14-,16+/m1/s1
InChIKey: RYAHJFGVOCZDEI-UFFNCVEVSA-N
- Boiling Point: 374.6±25.0 °C at 760 mmHg
- Melting Point: 135-136°C
- Solubility: In Vitro: DMSO : 33.33 mg/mL(126.55 mM;Need ultrasonic)In Vivo: 1.Add each solvent one by one: 10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% salineSolubility: ≥ 2.5 mg/mL (9.49 mM); Clear solution2.Add each solvent one by one: 10% DMSO >> 90% (20%SBE-β-CDin saline)Solubility: ≥ 2.5 mg/mL (9.49 mM); Clear solution3.Add each solvent one by one: 10% DMSO >> 90%corn oilSolubility: ≥ 2.5 mg/mL (9.49 mM); Clear solution
- Appearance: Cryst.
- Application: Analgesic/antipyretic
- Storage: 4°C, protect from light* In solvent : -80°C, 6 months-20°C, 1 month (protect from light)
Synonyms:
(3α,6α,7R,8S,9R,10α,11α)-Dendrobane-12-one; Dendroban-12-one; 12-Oxodendrobane; 7,5-(EpoxyMethano)-1H-cyclopent[cd]indol-9-one,decahydro-1,7b-diMethyl-6-(1-Methylethyl)-, (2aS,4aS,5R,6S,7R,7aS,7bR)-; Dendrobine Dendroban-12-one
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