Description:
MCC950, also called as CP-456773 or CRID3, is a small molecule that selectively inhibits activation of NLRP3 but does not inhibit NLRC4, AIM2, TLR2 signaling, or priming of NLRP3. MCC950 can be used to treat inflammatory diseases.
- Molecular Weight: 404.48
- Molecular Formula: C20H24N2O5S
Canonical SMILES:
CC(C)(C1=COC(=C1)S(=O)(=O)NC(=O)NC2=C3CCCC3=CC4=C2CCC4)O
InChI:
InChI=1S/C20H24N2O5S/c1-20(2,24)14-10-17(27-11-14)28(25,26)22-19(23)21-18-15-7-3-5-12(15)9-13-6-4-8-16(13)18/h9-11,24H,3-8H2,1-2H3,(H2,21,22,23)
InChIKey: HUUSXLKCTQDPGL-UHFFFAOYSA-N- Melting Point: 239 °C
- Solubility: Soluble to ≥ 28 mg/mL in DMSO
- Appearance: Light yellow to yellow solid
- Storage: Store in a cool and dry place and at 0 - 4°C for short term (days to weeks) or -66°C for long term (months to years).
Synonyms:
MCC-950; MCC 950; CP-456773
More details are to be found on supplier website
