Description:
Entecavir triphosphate is a highly potent inhibitor of wild-type HBV Pol and is 100- to 300-fold more potent than lamivudine triphosphate against 3TC-resistant HBV Pol. It competes with dGTP to be incorporated into viral DNA.
- Molecular Weight: 295.29
- Molecular Formula: C12H15N5O3.H2O
Purity: 98%
Canonical SMILES:
C=C1C(CC(C1CO)O)N2C=NC3=C2NC(=NC3=O)N.O
InChI:
InChI=1S/C12H15N5O3.H2O/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20;/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20);1H2/t6-,7-,8-;/m0./s1
InChIKey: YXPVEXCTPGULBZ-WQYNNSOESA-N
- Boiling Point: 661.4°C at 760 mmHg
- Melting Point: 31°C
- Solubility: In Vitro: DMSO: ≥ 32 mg/mL (108.37 mM)H2O: 2.8 mg/mL (9.48 mM; Need ultrasonic and warming)
- Appearance: White Powder
- Application: Antiviral Agents
- Storage: Store at -20°C
Synonyms:
Entecavir (monohydrate); UNII-5968Y6H45M; 5968Y6H45M
More details are to be found on supplier website
