Description:
Lipid 5 is a cationic amino lipid. LNPs incorporating Lipid 5 (from Sabnis et al.) demonstrated potent delivery of mRNA in primates but also were rapidly cleared from the body resulting in low toxicity.
- Molecular Weight: 710.18
- Molecular Formula: C44H87NO5
Purity: 95% by NMR/HPLC-ELSD
Canonical SMILES:
CCCCCCCCCOC(=O)CCCCCCCN(CCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCC)CCO
InChI:
InChI=1S/C44H87NO5/c1-4-7-10-13-16-25-32-41-49-43(47)35-28-21-17-23-30-37-45(39-40-46)38-31-24-18-22-29-36-44(48)50-42(33-26-19-14-11-8-5-2)34-27-20-15-12-9-6-3/h42,46H,4-41H2,1-3H3
InChIKey: ABCVHPIKBGRCJA-UHFFFAOYSA-N
- Solubility: Soluble in Ethanol, DMSO, DMF
- Storage: Store at -20°C
Synonyms:
Heptadecan-9-yl 8-((2-hydroxyethyl)(8-(nonyloxy)-8-oxooctyl)amino)octanoate
More details are to be found on supplier website
