Description:
ALC-0315 can be used to form lipid nanoparticle (LNP, non-viral gene delivery system).
- Molecular Weight: 766.27
- Molecular Formula: C48H95NO5
Purity: >98%
Canonical SMILES:
CCCCCCCCC(CCCCCC)C(=O)OCCCCCCN(CCCCCCOC(=O)C(CCCCCC)CCCCCCCC)CCCCO
InChI:
InChI=1S/C48H95NO5/c1-5-9-13-17-19-27-37-45(35-25-15-11-7-3)47(51)53-43-33-23-21-29-39-49(41-31-32-42-50)40-30-22-24-34-44-54-48(52)46(36-26-16-12-8-4)38-28-20-18-14-10-6-2/h45-46,50H,5-44H2,1-4H3
InChIKey: QGWBEETXHOVFQS-UHFFFAOYSA-N
- Boiling Point: 760.6±55.0 °C at 760 mmHg
- Solubility: In Vitro: DMSO : 50 mg/mL(65.25 mM;Need ultrasonic)Ethanol : 100 mg/mL(130.50 mM;Need ultrasonic)In Vivo: 1.Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% salineSolubility: ≥ 2.5 mg/mL (3.26 mM); Clear solution2.Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)Solubility: ≥ 2.5 mg/mL (3.26 mM); Clear solution3.Add each solvent one by one: 10% DMSO >> 90%corn oilSolubility: ≥ 2.5 mg/mL (3.26 mM); Clear solution
- Appearance: Colorless to Yellowish Oily Liquid
- Storage: Store at -20°C
Synonyms:
ALC-0315; ((4-Hydroxybutyl)azanediyl)bis(hexane-6,1-diyl) bis(2-hexyldecanoate)
More details are to be found on supplier website
