Description:
Diosbulbin B, a natural diterpenoid found in the roots of Dioscorea bulbifera, has hepatotoxicity, oral administration of DB for 12 consecutive days can lead to the oxidative stress liver injury in mice;ferulic acid prevents. Diosbulbin B exhibits the activity of anti-tumor and has inhibition of gastric cancer cell line SGC-7901 proliferation.
- Molecular Weight: 344.4
- Molecular Formula: C19H20O6
Purity: >95%
Canonical SMILES:
CC12CC(OC13CC(C4C2CC5CC4C(=O)O5)OC3=O)C6=COC=C6
InChI:
InChI=1S/C19H20O6/c1-18-6-13(9-2-3-22-8-9)25-19(18)7-14(24-17(19)21)15-11-4-10(5-12(15)18)23-16(11)20/h2-3,8,10-15H,4-7H2,1H3/t10-,11+,12+,13+,14-,15+,18-,19+/m0/s1
InChIKey: QEANLIISUSNNDX-YHPVUIEZSA-N
- Boiling Point: 574.8±50.0 °C(Predicted)
- Melting Point: 285 °C
- Appearance: Powder
- Application: antitumor
- Storage: 2-8°C
Synonyms:
(2R,3aS,6S,6aS,7R,10R,11aR,11bS)-2-(3-Furanyl)octahydro-11b-methyl-4H-3a,6: 7,10-dimethanofuro[2,3-c]oxepino[4,5-e]oxepin-4,8(6H)-dione8,12: 15,16-Diepoxy-19-nor-13(16),14-clerodadiene-17,6: 18,2-diolide.
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