Description:
Galantamine hydrobromide is a long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. It prevents β-amyloid-induced apoptosis in SH-SY5Y and bovine chromaffin cells.
- Molecular Weight: 368.28
- Molecular Formula: C17H21NO3.HBr
Purity: ≥95%
Canonical SMILES:
CN1CCC23C=CC(CC2OC4=C(C=CC(=C34)C1)OC)O.Br
InChI:
InChI=1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1
InChIKey: QORVDGQLPPAFRS-XPSHAMGMSA-N
- Melting Point: 255-256°C
- Solubility: Soluble in Methanol (Slightly, Sonicated), Water (Sparingly, Sonicated)
- Appearance: White to Off-white Solid
- Application: Nootropic Agents
- Storage: Store at -20°C
Synonyms:
6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, hydrobromide (1: 1), (4aS,6R,8aS)-; 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, monohydrobromide, (4aS,6R,8aS)-; Galanthamine, hydrobromide; (-)-Galantamine hydrobromide; (-)-Galanthamine hydrobromide; Galanthamine hydrogen bromide; Jilkon hydrobromide; Lycoremine hydrobromide; Nivalin; Nivaline; Nivaline (pharmaceutical); Razadyne; Reminyl; Tamilin
More details are to be found on supplier website
