Description:
Phase-I metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes.
- Molecular Weight: 407.42
- Molecular Formula: C24H19F2NO3
Purity: > 95%
Canonical SMILES:
C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(=O)C4=CC=C(C=C4)F)O
- Melting Point: >57 °C
- Appearance: White to Off-White Solid
Synonyms:
(3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone;
More details are to be found on supplier website
