Description:
Endomorphin 1 is a high affinity (Ki = 360 pM) and highly selective agonist of theμ-opioid receptor with 4000- and 15000-fold preference over δ and κ respectively and displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM.
- Molecular Weight: 610.7
- Molecular Formula: C34H38N6O5
Canonical SMILES:
C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CC5=CC=CC=C5)C(=O)N
InChI:
InChI=1S/C34H38N6O5/c35-26(17-22-12-14-24(41)15-13-22)34(45)40-16-6-11-30(40)33(44)39-29(19-23-20-37-27-10-5-4-9-25(23)27)32(43)38-28(31(36)42)18-21-7-2-1-3-8-21/h1-5,7-10,12-15,20,26,28-30,37,41H,6,11,16-19,35H2,(H2,36,42)(H,38,43)(H,39,44)/t26-,28-,29-,30-/m0/s1
InChIKey: ZEXLJFNSKAHNFH-SYKYGTKKSA-N- Boiling Point: 1052.8±65.0 °C at 760 Torr
- Melting Point: 144-146 °C
- Solubility: DMSO
- Application: Analgesics, Opioid
- Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms:
L-tyrosyl-L-prolyl-L-tryptophyl-L-phenylalaninamide
More details are to be found on supplier website
