Description:
Tipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS-102, which is an anticancer drug candidate currently in clinical trials. TAS-102 consists of the cytotoxin Trifluridine and the thymidine phosphorylase inhibitor (TPI) tipiracil. Trifluridine is incorporated into DNA during DNA synthesis and inhibits tumor cell growth. Tipiracil protects trifluridine from being broken down when taken orally.
- Molecular Weight: 279.121
- Molecular Formula: C9H12Cl2N4O2
Purity: 0.99
Canonical SMILES:
C1CC(=N)N(C1)CC2=C(C(=O)NC(=O)N2)Cl.Cl
InChI:
InChI=1S/C9H11ClN4O2.ClH/c10-7-5(12-9(16)13-8(7)15)4-14-3-1-2-6(14)11;/h11H,1-4H2,(H2,12,13,15,16);1H
InChIKey: KGHYQYACJRXCAT-UHFFFAOYSA-N
Synonyms:
Tipiracil, TPI.
More details are to be found on supplier website
