Description:
Valganciclovir hydrochloride hydrate is an antiviral used to treat cytomegalovirus infection. It is the prodrug of ganciclovir, a synthetic analog of 2'-deoxy-guanosine which is phosphorylated to a dGTP analog that competitively inhibits the incorporation of dGTP by viral DNA polymerase.
- Molecular Weight: 390.82
- Molecular Formula: C14H23ClN6O5
Purity: >98%
Canonical SMILES:
CC(C)C(C(=O)OCC(CO)OCN1C=NC2=C1NC(=NC2=O)N)N.Cl
InChI:
InChI=1S/C14H22N6O5.ClH/c1-7(2)9(15)13(23)24-4-8(3-21)25-6-20-5-17-10-11(20)18-14(16)19-12(10)22;/h5,7-9,21H,3-4,6,15H2,1-2H3,(H3,16,18,19,22);1H/t8?,9-;/m0./s1
InChIKey: ZORWARFPXPVJLW-MTFPJWTKSA-N
- Boiling Point: 629.1°C at 760 mmHg
- Melting Point: 162-164°C (dec.)
- Solubility: In vitro: 10 mM in DMSO
- Appearance: White Solid
- Storage: Powder: 3 years -20°CIn solvent: 2 years -80°C
Synonyms:
RS 079070-194; Ro 107-9070/194; Valcyte; (S)-Valganciclovir Hydrochloride
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