Description:
Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- Molecular Weight: 505.64
- Molecular Formula: C25H47NO9
Purity: >98.0%
Canonical SMILES:
CC(C)(C)OC(=O)CCOCC(COCCC(=O)OC(C)(C)C)(COCCC(=O)OC(C)(C)C)N
InChI:
InChI=1S/C25H47NO9/c1-22(2,3)33-19(27)10-13-30-16-25(26,17-31-14-11-20(28)34-23(4,5)6)18-32-15-12-21(29)35-24(7,8)9/h10-18,26H2,1-9H3
InChIKey: KPXODPHVWBQJEG-UHFFFAOYSA-N
- Solubility: 10 mm in DMSO
- Appearance: Colourless oil
- Storage: Store at -20 °C, keep in dry and avoid sunlight.
Synonyms:
Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane; tert-butyl 3,3'-(2-amino-2-((3-tert-butoxy-3-oxopropoxy)methyl)propane-1,3-diyl)bis(oxy)dipropanoate
More details are to be found on supplier website
