Description:
7-Deaza-2'-deoxy-7-iodoguanosine is a potent antiviral compound used in biomedicine. It exhibits antiviral activity against Herpes Simplex Virus (HSV) and Varicella-Zoster Virus (VZV). This nucleoside analogue acts by inhibiting viral DNA synthesis, making it effective in the treatment of HSV and VZV infections. It is commonly used in research and drug development related to antiviral therapies.
- Molecular Weight: 392.15
- Molecular Formula: C11H13IN4O4
Purity: ≥95%
Canonical SMILES:
C1C(C(OC1N2C=C(C3=C2N=C(NC3=O)N)I)CO)O
InChI:
InChI=1S/C11H13IN4O4/c12-4-2-16(7-1-5(18)6(3-17)20-7)9-8(4)10(19)15-11(13)14-9/h2,5-7,17-18H,1,3H2,(H3,13,14,15,19)/t5-,6+,7+/m0/s1
InChIKey: TVQBNMOSBBMRCZ-RRKCRQDMSA-N
- Boiling Point: 679.9±65.0°C at 760 mmHg
- Melting Point: >170°C (dec.)
- Solubility: Soluble in DMSO (Slightly, Heated, Sonicated), Methanol (Slightly, Heated, Sonicated)
- Appearance: White to Off-white Solid
- Storage: Store at -20°C under inert atmosphere
Synonyms:
2-Amino-7-(2-deoxy-b-D-ribofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-4(3H)-one; 7-Deaza-7-iodo-2'-deoxyguanosine; 2-Amino-7-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodo-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one; 7-iodo-7-deaza-2'-deoxyguanosine; 7-Iodo-2'-deoxy-7-carbaguanosine; 2-Amino-7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
More details are to be found on supplier website
