Description:
Zanubrutinib is a potent and irreversible BTK inhibitor. It is used as a medication for the treatment of Chronic Lymphocytic Leukemia.
- Molecular Weight: 471.55
- Molecular Formula: C27H29N5O3
Canonical SMILES:
C=CC(=O)N1CCC(CC1)C2CCNC3=C(C(=NN23)C4=CC=C(C=C4)OC5=CC=CC=C5)C(=O)N
InChI:
InChI=1S/C27H29N5O3/c1-2-23(33)31-16-13-18(14-17-31)22-12-15-29-27-24(26(28)34)25(30-32(22)27)19-8-10-21(11-9-19)35-20-6-4-3-5-7-20/h2-11,18,22,29H,1,12-17H2,(H2,28,34)/t22-/m0/s1
InChIKey: RNOAOAWBMHREKO-QFIPXVFZSA-N- Boiling Point: 713.4±60.0°C at 760 mmHg
- Solubility: Soluble in DMF, DMSO, Ethanol
- Appearance: Solid
- Application: Antineoplastic Agents
- Storage: Store at -20°C
Synonyms:
Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 4,5,6,7-tetrahydro-7-[1-(1-oxo-2-propen-1-yl)-4-piperidinyl]-2-(4-phenoxyphenyl)-, (7S)-; (7S)-4,5,6,7-Tetrahydro-7-[1-(1-oxo-2-propen-1-yl)-4-piperidinyl]-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide; Brukinsa; BGB-3111; BGB 3111; BGB3111
More details are to be found on supplier website
