Description:
LB-100 is a water-soluble protein phosphatase 2A (PP2A) inhibitor (IC50 = 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells) that enhanced the effects of sorafenib in HCC cells only during hypoxic environments.
- Molecular Weight: 268.31
- Molecular Formula: C13H20N2O4
Canonical SMILES:
CN1CCN(CC1)C(=O)C2C3CCC(C2C(=O)O)O3
InChI:
InChI=1S/C13H20N2O4/c1-14-4-6-15(7-5-14)12(16)10-8-2-3-9(19-8)11(10)13(17)18/h8-11H,2-7H2,1H3,(H,17,18)
InChIKey: JUQMLSGOTNKJKI-UHFFFAOYSA-N- Boiling Point: 486.9±45.0 °C at 760 Torr
- Solubility: H2O: ≥ 48 mg/mL; DMSO: < 2.9 mg/mL
- Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms:
(1S,4R)-2-(4-methylpiperazine-1-carbonyl)-7-oxabicyclo[2.2.1]heptane-3-carboxylic acid; LB 100; LB100
More details are to be found on supplier website
