Description:
Irofulven is a semisynthetic sesquiterpene derivative of illudin S, a natural toxin isolated from the fungus Omphalotus illudens. Irofulven alkylates DNA and protein macromolecules, forms adducts, and arrests cells in the S-phase of the cell cycle.
- Molecular Weight: 246.12
- Molecular Formula: C15H18O3
Purity: ≥95%
Canonical SMILES:
CC1=C(C2=C(C3(CC3)C(C(=O)C2=C1)(C)O)C)CO
InChI:
InChI=1S/C15H18O3/c1-8-6-10-12(11(8)7-16)9(2)15(4-5-15)14(3,18)13(10)17/h6,16,18H,4-5,7H2,1-3H3/t14-/m0/s1
InChIKey: NICJCIQSJJKZAH-AWEZNQCLSA-N
- Boiling Point: 501.0±45.0°C at 760 mmHg
- Melting Point: 127-129°C
- Solubility: Soluble in Chloroform (Slightly), Ethyl Acetate (Slightly)
- Appearance: Orange Solid
- Storage: Store at -20°C under inert atmosphere
Synonyms:
(6'R)-6'-Hydroxy-3'-(hydroxymethyl)-2',4',6'-trimethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one; (-)-(Hydroxymethyl)acylfulvene; (-)-Irofulven; HMAF; MGI 114; NSC 683863; 6-Hydroxymethylacylfulvene; Hydroxymethylacylfulvene; (R)-6'-Hydroxy-3'-(hydroxymethyl)-2',4',6'-trimethylspiro(cyclopropane-1,5'-(5H)inden)-7'(6'H)-one
More details are to be found on supplier website
