Description:
Cisplatin induces cytotoxicity by interaction with DNA to form DNA adducts which activate several signal transduction pathways, including Erk, p53, p73, and MAPK, which culminates in the activation of apoptosis. It is used in several types of cancer.
- Molecular Weight: 300.05
- Molecular Formula: Cl2H6N2Pt
Purity: >98%
Canonical SMILES:
[Cl-][Pt+2]([Cl-])([NH3])[NH3]
InChI:
InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
InChIKey: LXZZYRPGZAFOLE-UHFFFAOYSA-L
- Melting Point: 270°C
- Appearance: Orange to Yellow Powder
- Application: Antineoplastic agent
- Storage: Store at RT
Synonyms:
(SP-4-2)-diamminedichloro-platinum
More details are to be found on supplier website