Description:
Berberrubine comes from the herbs of Coptis chinensis Franch. Berberrubine dose-dependently inhibited IL-8 and MCP-1 protein levels in the media and mRNA expression of the cells stimulated with IL-1beta or TNF-alpha.
- Molecular Weight: 357.79
- Molecular Formula: C19H16ClNO4
Purity: >98%
Canonical SMILES:
COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)O.[Cl-]
InChI:
InChI=1S/C19H15NO4.ClH/c1-22-16-3-2-11-6-15-13-8-18-17(23-10-24-18)7-12(13)4-5-20(15)9-14(11)19(16)21;/h2-3,6-9H,4-5,10H2,1H3;1H
InChIKey: GYFSYEVKFOOLFZ-UHFFFAOYSA-N
- Appearance: Red needles
- Application: Antitumor/anti-diabetic
Synonyms:
5,6-Dihydro-9-hydroxy-10-methoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium chloride; 9-Berberoline chloride; 9-Demethoxy-9-hydroxyberberinium chloride; Berberrubine chloride; Beroline chloride; Chileninone; Nerberrubine
More details are to be found on supplier website