Description:
BLU9931 is a potent and irreversible small-molecule inhibitor of FGFR4, as a targeted therapy to treat patients with HCC whose tumors have an activated FGFR4 signaling pathway. BLU9931 is exquisitely selective for FGFR4 versus other FGFR family members and all other kinases.
- Molecular Weight: 509.38
- Molecular Formula: C26H22Cl2N4O3
Purity: 98%
Canonical SMILES:
C=CC(NC1=CC=CC(C)=C1NC2=NC=C3C=C(C4=C(Cl)C(OC)=CC(OC)=C4Cl)C=CC3=N2)=O
InChI:
InChI=1S/C26H22Cl2N4O3/c1-5-21(33)30-18-8-6-7-14(2)25(18)32-26-29-13-16-11-15(9-10-17(16)31-26)22-23(27)19(34-3)12-20(35-4)24(22)28/h5-13H,1H2,2-4H3,(H,30,33)(H,29,31,32)
InChIKey: TXEBNKKOLVBTFK-UHFFFAOYSA-N
- Solubility: Soluble in DMSO, not in water
- Appearance: Solid powder
- Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Synonyms:
BLU9931; BLU-9931; BLU 9931.
More details are to be found on supplier website
